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Reference and calibration standards for environmental testing protocols; includes water, wastewater, EPA, TOC, DOD and other laboratory and environmental chemical standards.
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Tioconazole (65899-73-2) is a small-molecule inhibitor targeting the fungal cytochrome P450-dependent enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane stability and cellular integrity Tioconazole exerts its biological activity primarily through interference with ergosterol biosynthesis within fungal cell membranes In in vitro studies Tioconazole demonstrates inhibitory activity with MIC50 values below 3 12 mg/L for dermatophyte strains and below 9 mg/L for yeast species Based on these pharmacological properties Tioconazole holds research potential in the study of antifungal mechanisms and in vitro antifungal screening assays
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Deoxyribonuclease I from Bovine Pancreas min. 3000 Kunitz units/mg lyophil. Cleaves preferentially double-stranded DNA (in the presence of Mg++-ions single stranded DNA) in oligonucleotides with 5'-terminal phosphate groups. Size - 25MG Storage Conditions - -15 °C TO -25 °C Catalog Number - 18535.01
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Arbutin (CAS 497-76-7) is a naturally occurring glycosylated hydroquinone primarily isolated from bearberry (Arctostaphylos uva-ursi) leaves It acts as a competitive inhibitor of tyrosinase an enzyme central to melanin biosynthesis thereby modulating pigment production in biological systems Arbutin is extensively studied in cellular and biochemical assays investigating melanogenesis oxidative stress and potential antimelanogenic therapies Its ability to regulate melanin synthesis has made it a valuable research tool in dermatology cosmetic science and pharmacological studies focused on hyperpigmentation and related disorders The compound should be stored in a sealed cool and dry environment to maintain stability
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PTP Inhibitor I (CAS 2491-38-5) is a small molecule inhibitor targeting protein tyrosine phosphatases (PTPs) specifically SHP-1 and PTP1B with inhibition constants (KI) of 43 M and 42 M respectively As an -bromoacetophenone derivative it acts as a neutral phosphotyrosine mimetic covalently modifying the active site cysteine of PTPs Structure-activity studies indicate that modifications to the phenyl ring moderately affect potency while para-substituted peptidyl groups can enhance both potency and selectivity PTP Inhibitor I is utilized in vitro for mechanistic studies of PTP function related to diabetes neurodegenerative disorders immune regulation and pathogen virulence Animal and clinical data are not available
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Tolfenamic acid (CAS 13710-19-5) is a non-steroidal anti-inflammatory drug (NSAID) that functions primarily through the inhibition of cyclooxygenase (COX) enzymes resulting in reduced prostaglandin synthesis and inflammation In cellular studies tolfenamic acid has been observed to inhibit cell proliferation and promote apoptosis as indicated by heightened caspase activity and alterations in bioelectric impedance measurements These findings support its utility in research investigating inflammatory pathways apoptosis induction and the cellular effects of NSAIDs in various biological systems
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Prilocaine hydrochloride (CAS 1786-81-8) is a local anesthetic belonging to the amino amide class It functions by reversibly inhibiting voltage-gated sodium channels on neuronal cell membranes thereby blocking the initiation and propagation of nerve impulses This property makes it suitable for investigating neuronal excitability pain signaling and ion channel pharmacology in various preclinical models Prilocaine hydrochloride is commonly employed in studies requiring local anesthesia and serves as a reference compound for benchmarking novel anesthetic agents in research settings
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Amoxicillin Sodium (CAS 34642-77-8) is a small-molecule inhibitor targeting bacterial cell wall biosynthesis It is designed to disrupt peptidoglycan formation thereby compromising bacterial cell wall integrity Amoxicillin Sodium exerts its biological activity primarily through inhibition of peptidoglycan biosynthesis leading to bacterial lysis and cell death In in vitro studies Amoxicillin Sodium demonstrates broad-spectrum antibacterial inhibitory activity with IC50 values ranging from 0 1 g/mL to 10 g/mL depending on bacterial strain variability and experimental conditions Based on these pharmacological properties Amoxicillin Sodium holds research potential in bacterial physiology characterization antibiotic resistance evaluations and in vitro infection modeling studies
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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Diclofenac potassium (CAS 15307-81-0) is a synthetic small molecule belonging to the nonsteroidal anti-inflammatory drug (NSAID) class It functions primarily by inhibiting cyclooxygenase (COX) enzymes thereby reducing the synthesis of prostaglandins involved in inflammation and nociception Through this mechanism diclofenac potassium attenuates inflammatory responses and mediates analgesic effects It is frequently utilized in biomedical research to study inflammatory pathways investigate mechanisms of pain modulation and evaluate anti-inflammatory interventions in cellular and preclinical models
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